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2021 | 2 |
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Page 1
The ins and outs of serine and glycine metabolism in cancer.
Nat Metab. 2021 Feb;3(2):131-141. doi: 10.1038/s42255-020-00329-9. Epub 2021 Jan 28.
Nat Metab. 2021.
PMID: 33510397
Review.
Transcription factor NKX2-1 drives serine and glycine synthesis addiction in cancer.
Heylen E, Verstraete P, Van Aerschot L, Geeraerts SL, Venken T, Timcheva K, Nittner D, Verbeeck J, Royaert J, Gijbels M, Uyttebroeck A, Segers H, Lambrechts D, Cools J, De Keersmaecker K, Kampen KR.
Heylen E, et al. Among authors: geeraerts sl.
Br J Cancer. 2023 May;128(10):1862-1878. doi: 10.1038/s41416-023-02216-y. Epub 2023 Mar 17.
Br J Cancer. 2023.
PMID: 36932191
Free PMC article.
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Repurposing the Antidepressant Sertraline as SHMT Inhibitor to Suppress Serine/Glycine Synthesis-Addicted Breast Tumor Growth.
Geeraerts SL, Kampen KR, Rinaldi G, Gupta P, Planque M, Louros N, Heylen E, De Cremer K, De Brucker K, Vereecke S, Verbelen B, Vermeersch P, Schymkowitz J, Rousseau F, Cassiman D, Fendt SM, Voet A, Cammue BPA, Thevissen K, De Keersmaecker K.
Geeraerts SL, et al.
Mol Cancer Ther. 2021 Jan;20(1):50-63. doi: 10.1158/1535-7163.MCT-20-0480. Epub 2020 Nov 17.
Mol Cancer Ther. 2021.
PMID: 33203732
Free PMC article.
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